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Our Lab

investigates the interplay between immune cells and various disease including cancer and inflammation in vivo. Our aim is to understand the mechanism that control immunity and to identify novel targets for cancer immunotherapy.

We focussing on (1) CAR t-cells and (2) neutrophile extracellular traps (NETs).


Pediatric Tumors are particularly immunogenic. We develop and implement cutting-edge CAR t-cell technologies to control or eliminate cancer and to modulate the immune system. In our lab we combine  and  into novel therapeutic strategies which will ultimately benefit children suffering from cancer or immune disease.

NETs confer protection against infections, but also drive inflammation and immunopathology.

Latest Publications

iScience: Peritoneal adhesions are highly prevalent but poorly understood conditions. Neutrophil Extracellular Traps (NETs) are the base for peritoneal adhesions in experimental murine models and human biopsies. Dornase alfa (DNase1) and the human DNase1l3 analog NTR-10 are promising therapeutic agents.

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